MACHEREY-NAGEL Polygram Silgur UV254 Pre-Coated TLC Polyester Sheet

Description

Product Overview

The MACHEREY-NAGEL Polygram Silgur G UV254 pre‑coated TLC sheet is engineered for high‑precision thin‑layer chromatography in demanding laboratory environments. Each plate measures 4 × 8 cm and is fabricated from a robust polyester substrate that resists warping, chemical attack, and mechanical stress. The surface is uniformly coated with a silica‑gel layer that has been impregnated with a UV‑254 absorbing additive, providing exceptional protection against background fluorescence and enabling clear visualization of analytes under UV illumination. The product is supplied in a convenient pack of 50 plates, ensuring a consistent supply for repetitive analytical workflows. Manufactured in Germany under strict quality‑control protocols, the sheets meet international standards for chromatographic performance and are compatible with a wide range of mobile phases, detection methods, and sample types.

Usage

These TLC sheets are ideal for applications ranging from pharmaceutical impurity profiling and natural product isolation to environmental monitoring and forensic analysis. The UV‑254 pre‑coating allows analysts to perform rapid spot detection without the need for additional staining reagents, reducing assay time and chemical waste. The plates perform reliably in both low‑temperature and elevated‑temperature conditions, making them suitable for ambient laboratory work as well as controlled‑temperature chambers. Users can employ the sheets in standard TLC chambers, automated development systems, or custom‑built apparatuses, and they are compatible with both manual spotting techniques and robotic sample applicators. The 4 × 8 cm format provides ample surface area for multiple sample lanes while maintaining a compact footprint for efficient storage.

Why Choose Us

Choosing the MACHEREY‑NAGEL Polygram Silgur series means selecting a product backed by decades of expertise in chromatography media development. The polyester base offers superior durability compared with traditional glass or cellulose supports, reducing the risk of breakage and extending the usable life of each plate. The UV‑254 additive is integrated during the coating process, guaranteeing uniform distribution and consistent optical properties across the entire batch. Each lot undergoes rigorous batch‑to‑batch verification, including plate thickness measurement, silica‑gel uniformity assessment, and UV absorbance testing, ensuring that every sheet delivers reproducible migration distances and spot shapes. In addition, the manufacturer provides comprehensive technical support, detailed application notes, and a responsive customer service team that can assist with method development, troubleshooting, and regulatory compliance questions.

Key Features

• Durable polyester substrate resists cracking and chemical degradation for long‑term storage.
• UV‑254 pre‑coating eliminates background fluorescence, enabling clear spot detection without extra reagents.
• Uniform silica‑gel layer provides consistent capillary flow and reproducible Rf values across all plates.
• Standard 4 × 8 cm size fits most TLC chambers while offering multiple lanes for high‑throughput analysis.
• Pack of 50 ensures a reliable supply and reduces per‑plate cost for routine laboratory use.
• Manufactured in Germany under ISO‑9001 quality management for traceable batch consistency.
• Dedicated technical support and application guidance available from the supplier.

FAQ

What types of samples can be analyzed on these TLC sheets?

The sheets are suitable for a broad range of organic, pharmaceutical, environmental, and biochemical samples, including small molecules, natural extracts, pigments, and polymers. Compatibility with both polar and non‑polar mobile phases allows flexible method development.

Can the plates be reused after analysis?

While the plates are designed for single‑use applications to maintain analytical integrity, they can be regenerated for certain qualitative tests by thorough cleaning and re‑coating, though this is not recommended for quantitative work.

How does the UV‑254 pre‑coating affect detection sensitivity?

The integrated UV‑254 additive suppresses background fluorescence, which enhances the signal‑to‑noise ratio when visualizing spots under UV light, allowing detection of low‑concentration analytes without additional staining.

Are the plates compatible with automated spotting instruments?

Yes, the flat, uniform surface of the polyester sheets is fully compatible with robotic sample applicators and high‑throughput TLC dispensers, facilitating reproducible spot placement and volume control.

What storage conditions are recommended to preserve plate quality?

Store the plates in a cool, dry environment away from direct sunlight and strong solvents. Sealed packaging helps maintain moisture balance and prevents contamination, ensuring consistent performance over the shelf life.